mTOR mRNA transport

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mRNA_transport_axons

The top shows the structure of the mTOR mRNA with the 5’untranslated region (5′-UTR), the coding region, and the 3′-UTR. The 3′-UTR of the mTOR messenger RNA has a structure that is recognized by an RNA-binding protein. In the lower part of the image, the RNA-binding protein enables the transport of the mRNA by a microtubule motor protein so that mTOR transcripts are delivered to the injured part of the axon to mediate local synthesis of mTOR protein.

Read more: N. R. Gough, The mTOR-Dependent Translatome in Growing Nerves and Injured Axons. BioSerendipity (18 February 2019)
https://www.bioserendipity.com/the-mtor-dependent-translatome-in-growing-nerves-and-injured-axons/.

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