The image shows the crystal structure of the part of the TLR7 protein that interacts with viral RNA. The pink and blue subunits each bind to viral RNA and then interact with each other to form the complex shown. What are not shown are the transmembrane domains and the signaling parts of the proteins that extend into the cytoplasm of the cell. These viral RNA-binding domains are found inside endosomes and lysosomes in immune cells that take up cellular debris and viral particles. The structure is from PDB 5ZSF.
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