Discovery of a Pan-Cancer Killing T Cell

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Crowther and colleagues screened clones of T cells isolated from a healthy donor and identified a clone (MC.7.G5) that recognized and killed many different types of cancer cells, including cells from solid tumors. When mixed with lung, melanoma, leukemia, breast, colon, prostate, bone, or ovarian cancer cell lines, MC.7.G5 released tumor necrosis factor (TNF) and … Read more

Using Flu Vaccines to Treat Cancer

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Researchers discovered that injecting inactive flu virus directly into solid tumors triggered a systemic anti-tumor immune response. Thus, seasonal flu vaccines or other inactivated virus vaccines could be repurposed as agents that convert immune “cold” tumors into immune hot ones.  Newman and colleagues found that influenza infection, which is respiratory virus that infects the lungs, … Read more

A Cryobank for T Cells

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As cancer therapies increasingly include using the patient’s own immune cells to fight the cancer, a new product has emerged on the market. Cell Vault is a new company that will send anyone a blood collection kit, draw the blood either at home or in an office, and then store the processed sample frozen in … Read more

Worth a Closer Look: May 2019

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A list of papers published in May 2019 that piqued my interest

Worth a Closer Look: April 2019

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As I was selecting the articles related to proteomics and disease, I kept a running list of those that piqued my interest. These range in topic and are not all related to proteomics. Most are related to medicine or human disease. Hopefully, I will have time to take a closer look at them all and … Read more