Therapeutic approaches to manipulating the immune system to treat cancer
Crowther and colleagues screened clones of T cells isolated from a healthy donor and identified a clone (MC.7.G5) that recognized and killed many different types of cancer cells, including cells from solid tumors. When mixed with lung, melanoma, leukemia, breast, colon, prostate, bone, or ovarian cancer cell lines, MC.7.G5 released tumor necrosis factor (TNF) and … Read more
As cancer therapies increasingly include using the patient’s own immune cells to fight the cancer, a new product has emerged on the market. Cell Vault is a new company that will send anyone a blood collection kit, draw the blood either at home or in an office, and then store the processed sample frozen in … Read more
As I was selecting the articles related to proteomics and disease, I kept a running list of those that piqued my interest. These range in topic and are not all related to proteomics. Most are related to medicine or human disease. Hopefully, I will have time to take a closer look at them all and … Read more
A list of articles classified by Nancy R. Gough as good, valuable contributions or not so valuable contributions to the scientific literature.
Antibodies are proteins. In the body, they are made by B cells of the immune system. To produce antibodies as therapeutics, they are synthesized by cells in culture. The structure of an antibody is defined by the amino acid sequence of the protein (Figure 1). The incredible diversity of antibodies, which is essential to our … Read more