Function, regulation, and manipulation of the immune system and inflammatory responses
The following papers piqued my interest this week. Hopefully, I will have time to take a closer look at them all and decide which ones warrant a thumbs up and which ones a thumbs down. Some I found through my Biomed News search of the proteomics and disease list, some through social media, and some … Read more
A list of articles classified by Nancy R. Gough as good, valuable contributions or not so valuable contributions to the scientific literature.
Graft-versus-host disease (GVHD) is occurs in people who have received bone marrow or blood stem cell transplants from donors (allogenic transplants). The donated cells replace the stem cells that make the cells of the immune system and red blood cells in patients with leukemias or lymphomas or various types of bone marrow diseases, blood disorders, … Read more
As someone who recently had the distinctly unpleasurable experience of shingles, I decided to research the vaccines available for this viral disease. Shingles is caused by varicella zoster virus (VZV), which also causes chicken pox (Figure 1). VZV is a type of herpes virus. Presently, in the US, most children are vaccinated against chicken pox. … Read more
A type of immunotherapy uses antibodies that activate the TNF receptor family member CD40 on immune cells. CD40 is present on antigen-presenting cells (APCs) of the immune system and is activated by surface-bound proteins called CD40L. Activation of CD40 on APCs stimulates these cells to take up and display antigens to T and B cells, … Read more