Posttranslational Modifications
Worth a Closer Look: April 2019
As I was selecting the articles related to proteomics and disease, I kept a running list of those that piqued my interest. These range in topic and are not all related to proteomics. Most are related to medicine or human disease. Hopefully, I will have time to take a closer look at them all and … Read more
Yeast Study Links Arsenic to Diabetes through Glucose Transporters
Yeast are a genetically tractable model system to study various aspects of cellular physiology or toxicology. In the study by Jochem and colleagues, the researchers investigated a potential mechanism for a connection between arsenic exposure and type 2 diabetes by analyzing the effects of arsenic exposure in yeast. This study is a follow up to … Read more
A Closer Look: 10 March 2019
A list of articles classified by Nancy R. Gough as good, valuable contributions or not so valuable contributions to the scientific literature.
Building Better Antibodies
Antibodies are proteins. In the body, they are made by B cells of the immune system. To produce antibodies as therapeutics, they are synthesized by cells in culture. The structure of an antibody is defined by the amino acid sequence of the protein (Figure 1). The incredible diversity of antibodies, which is essential to our … Read more