A T cell engineered to recognize a tumor antigen and to produce an antibody that inhibits the immune checkpoint. The cell represents a chimeric antigen receptor (CAR) T cell that also produces one or more antibodies against PD-1, PD-L1, or CTLA-4. Antibody image by Gentaur via Wikimedia Commons. Compilation by Nancy R. Gough, Bioserendipity, LLC
Read more at
N. R. Gough, Making Immune “Cold” Tumors Hot. BioSerendipity (31 May 2017). https://www.bioserendipity.com/making-immune-cold-tumors-hot/