Alkylglycerol lipids (AKGs) are ingested in breast milk. Macrophages in fat tissue convert AKG molecules into platelet-activating factor (PAF). PAF binds its receptor on the macrophages to stimulate the production and release of interleukin 6 (IL-6). IL-6 stimulates expression of the beige adipose gene profile to maintain thermogenic adipose tissue in breastfed newborns. [Credit: Nancy R. Gough, BioSerendipity, LLC]
Read more:
N. R. Gough, Signal or Nutrient: Breast Milk Lipids in Macrophages. BioSerendipity (December 2019) https://www.bioserendipity.com/signal-or-nutrient-breast-milk-lipids-in-macrophages
N. R. Gough, Researchers Find a Special Lipid that Controls Fat Development in Babies. Medium (18 October 2019).