Some friends asked me about an anti-aging supplement called Basis by Elysium Health. This prompted me to look into the biology behind the two “active” ingredients in this and other anti-aging dietary supplements. The compounds are nicotinamide riboside and pterostilbene. Pterostilbene is chemically related to resveratrol; both are bioactive components found in certain berries, grapes, … Read more
Some anti-aging supplements include compounds, like nicotinamide riboside, that increase nicotinamide adenine dinucleotide (NAD: oxidized NAD+ and reduced NADH) and stilbenoid compounds, like resveratrol or pterostilbene, that are anti-oxidants and regulators of protein function. The findings that resveratrol inhibited human platelet aggregation and prevented cancer cell proliferation in culture and cancer in mice created excitement … Read more
Cellular and whole-body metabolism changes with age. An emerging idea is that preventing these metabolic changes may reduce negative effects of aging or at least delay them. Indeed, this idea is popular enough that companies are developing and selling dietary supplements intended to boost “healthy” metabolism. Many are intended to boost the amount of a … Read more
Vitamins and nutrients in foods are key to maintaining a healthy life. Research in many areas has converged on the idea that altered metabolism is a key factor in aging and aging-associated diseases. Consequently, there is great interest in identifying molecules in food that can support a youthful, healthy metabolism and thus reduce aging-associated disease … Read more