The Power of Proteomics in Building the Human Protein Interaction Network
Defining >56,000 Human Protein Interactions through Mass Spectrometry Huttlin and colleagues applied mass spectrometric analysis to affinity purified protein complexes to help build a partial reference map of the human protein interaction space (1). The cDNA encoding the target proteins also engineered to have affinity tags (hemagglutinin and FLAG) were introduced into an easily infected … Read more