mass cytometry

Single-Cell Proteomics Shines Light on the Complexity of Immune Cells in Solid Tumors

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Phenograph_clustering_example

A Proteomic Approach to the Tumor Microenvironment An outstanding issue in treating solid cancers is understanding the complexity of this pathological tissue. Solid tumors are comprised not only of the cancer cells, but they also contain immune cells, cells that form blood vessels and lymphatic vessels, fibroblasts, and the stem cells that form the fibroblasts … Read more

Fighting Cancer with the Immune System: Lessons from CAR T Cell Therapy

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CAR-T-cell-killing-cancer-cell-illustration

The Promise of CAR T Cell Therapy Many strategies that train the immune system to recognize and attack cancer are in development or undergoing clinical trials (1). However, these strategies have the potential to cause life-threatening consequences, as evidenced by the latest report of the death of another patient receiving CAR T cell therapy (2). CAR … Read more