Drug Repurposing: Preserving Vision with New Drug Combinations

medicines

Overcoming side effects and toxicity of currently FDA-approved is possible. Sometimes combining multiple drugs with different mechanisms of action lets doctors use less of each drug to achieve the desired effect and limit or avoid off-target or dose-limiting effects. This is a common strategy used for anesthesia. Doctors give a “cocktail” of drugs with different … Read more

Drug Repurposing: Preventing Blindness with an Antifungal

Macular_degeneration

Benefits of Off-Target Effects There are many FDA-approved medicines. Most have some “off-target” effects, meaning effects that are not those intended for the drug. Sometimes these off-target effects limit the dose of a drug that can be used to treat the intended disease or symptom.  Sometimes these off-target effects are unwanted side effects that the … Read more