Structure of pyroglutamate-modified amyloid-beta bound to an antibody. Blue is the amyloid-beta peptide that binds deep in a v-shaped pocket on the antibody. From PDB: 5MYX.
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N. R. Gough, Targeting Pyroglutamate Aβ in Alzheimer’s Disease. BioSerendipity (6 September 2017) https://www.bioserendipity.com/targeting-pyroglutamate-aB-in-alzheimers-disease/